Tijuana is a mystical city and the scene of different stories, where the characters search for meaning in their lives.
During the mid-1970s, in the Mexican state of Guanajuato, authorities discover a clandestine burial ground. The corpses are from murdered prostitutes. The suspects are three sisters known as "Las Poquianchis".
In the colonial New Spain Ana is a missionary who decides to support the indigenous people.